The project is funded by the Seventh Framework Programme of the European Commis. Simultaneously SPECT and MR images of the brain and improve personalized treatment of As the name suggests, the research project aims to develop, test,Īnd validate a SPECT insert for commercially available MRI scanners, in order to acquire The acronym INSERT stands for IN tegrated SPECT/MRI for Enhanced stratification in RadiochemoTherapy.

INSERT, this chapter summarizes the achieved technical developments and the status of the Of interaction to reduce the error in the localisation of the photon’s path and improveĭue to the close proximity of the topics discussed in this thesis and the European project For a slit-slat collimator, parallax is worse for smallĭistances from the slit plane to the object, leading to parallax blur which can severely affectĪ solution to reduce parallax effects is to use a thin crystal, but then only a smallįraction of gamma-rays can be detected, or use the information about the photon’s depth Furthermore parallax can lead to multiplexingĪnd consequently poor image quality. However for particularly acute incident angles of the gamma-rays onto theĬrystal, the interaction can take place in a large range of depths in the crystal, leading to anĮrroneous detection direction (Figure 2.10). For gamma-rays hitting the crystal perpendicularly or inĪ near-to-perpendicular direction, the uncertainty associated with the detection point is Will attribute each gamma-ray to a different ray path and this information will be used Tion crystal or sensitive volume before causing ionization and being detected. Parallax errors relate to the uncertainty of how deep gamma-rays penetrate the scintilla.

The thick dashed line divides the crystal in two halves. Path is represented by the dashed line, and the uncertainty in the detection point by As a result, the image quality deteriorates,Īlthough sensitivity might improve due to the multiple pinholes.įigure 2.10: Parallax error (left) and improvement (right) using DOI information. Object being imaged (Barrett and Hunter, 2005). This means that the photons are less specific and carry less information about the The projected gamma-rays through the pinholes onto the detector surface might occur.Ĭonsequently there will be uncertainty about which pinhole the detected gamma-rays came For example, when imaging with a multi-pinhole collimator, overlap between Multiplexing is a phenomenon related to the ambiguity in the origin of the projected

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